Leading GnRH Offers More Doses for Greater Efficiency

New 15-dose bottle available from CYSTORELIN® (gonadorelin diacetate tetrahydrate)

The new 15-dose bottles of CYSTORELIN come in a new blue carton with 10 bottles per carton. One new carton of 15-dose CYSTORELIN (containing 150 doses) requires the same amount of refrigerator space as ten 5-dose cartons (50 doses).

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DULUTH, GA — January 13, 2010 — CYSTORELIN, the No. 1 selling1 gonadotropin-releasing hormone (GnRH) is now available in a new 15-dose bottle. No other GnRH currently offers as many doses in one bottle.

CYSTORELIN treats ovarian follicular cysts, which activates the process leading to estrus.2 This presents a number of reproductive advantages for producers.

“Reproduction is one of the most important aspects to any cattle operation, so the smallest improvements can mean big returns,” says Dr. Tom Van Dyke, manager, Merial Veterinary Services. “Any chance to help improve breeding is an opportunity that should be taken advantage of.”

One of these improvements, he explains, is upgrading to the larger 15-dose bottle of CYSTORELIN because of the number of advantages it offers.

“More doses of CYSTORELIN per bottle helps producers treat more cows at once — saving them valuable time and money in an economy where every dollar counts,” Dr. Van Dyke says. “And, with less bottles and packaging to dispose of, this herd health product has become more environmentally friendly.”

He also explains that a larger bottle can be even more efficient if administered with a multidose syringe — allowing producers to treat a group without switching bottles every few cows.

“Producers do as much as they can to make their operations as efficient as possible, but there’s always room for improvement,” Dr. Van Dyke says. “CYSTORELIN in a large 15-dose bottle can help seal up cracks in a reproductive program where profits could be seeping through.”

Efficient administration and waste control are just the beginning when it comes to the profits that can be saved. Dr. Van Dyke adds that CYSTORELIN is the most effective at inducing an ovulatory response,2 which can lead to a decrease in missed pregnancies and days open.

CYSTORELIN induces ovulation by treating ovarian follicular cysts — a leading cause of reproductive failure.3 Follicular cysts leave cows infertile as long as the condition persists, causing major production losses.3 Ovarian follicular cysts are estimated to affect at least 1 million cows in the United States annually and can cause a number of reproductive issues such as extended calving intervals and infertility.3

“Each missed pregnancy can cost a producer up to $450,”4 Dr. Van Dyke says. “And, with fertility rates on the decline, producers who aren’t using CYSTORELIN to boost their reproductive program may be hurting their bottom line.”

If producers are still on the fence about whether or not to include a GnRH in their breeding protocol, Dr. Van Dyke suggests they consider the multitude of benefits.

“CYSTORELIN can help treat ovarian cysts to help induce ovulation and keep herds calving on a profitable schedule,” Dr. Van Dyke says. “Whether producers choose the new 15-dose or stick with the 5-dose bottle, keeping herds calving is a major benefit that any producer can’t ignore.”

For more information about CYSTORELIN, or for a Spanish/English training guide to use with employees, call 1-888-637-4251.

Merial is a world-leading, innovation-driven animal health company, providing a comprehensive range of products to enhance the health, well-being and performance of a wide range of animals. Merial employs approximately 5,700 people and operates in more than 150 countries worldwide. Its 2009 sales were over $2.6 billion. Merial is the Animal Health subsidiary of sanofi-aventis. For more information, please see