LONGRANGE® (eprinomectin) Approved for Protection Against Additional Roundworms

Following extensive study, Merial announces that LONGRANGE® (eprinomectin) has received approval by the FDA’s Center for Veterinary Medicine for the treatment and control1 of Bunostomum phlebotomum, a gastrointestinal roundworm found in beef and dairy cattle. In addition, the extended-release dewormer protects cattle from reinfection of the worm for 150 days following treatment.1
In five dose confirmation studies, LONGRANGE was found to be 100% effective for the treatment and control of B. phlebotomum (adults and larval stages [L4]).1
In a U.S. persistency study, LONGRANGE was shown to be 99.8% effective against the parasite 150 days after treatment, as well as 95.6% 150 days post-treatment in a European study. Additionally, it was found to be 95 to 100% effective in three clinical field studies.1
The parasite can be a serious threat to herds, especially in warm, moist areas. If infected, cattle, especially the young, may grow poorly and not thrive.2
When administered at the recommended dose volume of 1 mL per 110 lbs. of body weight, LONGRANGE is effective in the treatment and control of certain internal and external parasites, including gastrointestinal roundworms and lungworms, for up to 150 days with a single dose.3
Merial continues to work to add additional indications to LONGRANGE to reflect the product’s spectrum, efficacy and persistency.
LONGRANGE is the first extended-release injection that delivers up to 150 days of parasite control in a single dose, thanks to its unique formulation3 (THERAPHASE™).  A single spring treatment of LONGRANGE works long enough to break the parasite life cycle and reduce pasture reinfection.4,5 LONGRANGE is available through a prescription from a veterinarian.
IMPORTANT SAFETY INFORMATION: Do not treat within 48 days of slaughter. Not for use in female dairy cattle 20 months of age or older, including dry dairy cows, or in veal calves. Post-injection site damage (e.g., granulomas, necrosis) can occur. These reactions have disappeared without treatment.
1FOI Summary.
2Taylor MA, Coop RL, Wall RL. Vet Parasitol. 3rd ed. 2007:64-65.
3LONGRANGE product label.
4Morley FH, Donald AD. Farm management and systems of helminth control. Vet Parasitol. 1980;6: 105-134.
5Brunsdon RV. Principles of helminth control. Vet Parasitol. 1980;6: 185-215.