Ready To Go EXCENEL® RTU EZ Is Now Easier To Use

 An innovative, easier-to-use version of a popular anti-infective is now available for veterinarians and their cattle and swine producer clients. Zoetis introduces EXCENEL® RTU EZ (ceftiofur hydrochloride) Sterile Suspension with a lower viscosity formulation that improves syringeability by 40 percent. 1
“EXCENEL RTU has a 20-year history as an effective, fast-acting treatment, offering a short meat withdrawal for cattle and swine and zero milk withholding for dairy cattle. Still, we recognized there was an opportunity to further improve syringeability to help ease of use by veterinarians and producers,” said Matthew Helpern, marketing manager, swine injectable anti-infectives, Zoetis. “The new formulation was designed with our customers in mind. EXCENEL RTU EZ is now easier to get out of the bottle and into your animals when they need it.”
To improve ease of use, EXCENEL RTU EZ takes advantage of a lower viscosity formula. With the improved syringeability, users of EXCENEL RTU EZ will only need to apply 60 percent of the force required to administer the previous formulation. 1 Producers and veterinarians will especially notice the change during colder weather.
The improved EXCENEL RTU EZ offers the same approved uses for which the brand is known. Veterinarians, as well as their cattle and pork producer clients, can use EXCENEL RTU EZ as an effective solution for:

  • Treatment of bovine respiratory disease (BRD), pneumonia, shipping fever
  • Control and treatment of swine respiratory disease (SRD)
  • Treatment of foot rot (all cattle)
  • Treatment of acute, postpartum metritis (dairy cattle only)

The only changes customers will note are in the meat withdrawal for cattle and the administration for swine.
·         For cattle, EXCENEL RTU EZ has a four-day meat withdrawal. The new withdrawal period is the same as NAXCEL® (ceftiofur sodium) Sterile Powder and is still one of the shortest in its class.
·         For swine, do not inject more than 5 mL of EXCENEL RTU EZ per injection site.
Producers should work with their veterinarian to review protocols and make necessary adjustments in animal health management. Even with these changes, EXCENEL RTU EZ is still backed by the Residue Free Guarantee™* in both cattle and swine.
“We’re excited about the evolution of this important treatment solution, but we need producers and veterinarians to pay special attention to the meat withdrawal and injection restrictions,” said Matt Nelson, senior marketing manager, cattle anti-infectives, Zoetis. “These changes are not dramatic, but we’re asking our customers to update their existing animal health systems when incorporating EXCENEL RTU EZ into protocols.”
EXCENEL RTU EZ is easy to use and ready to go. Learn more about EXCENEL RTU EZ by contacting your veterinarian or Zoetis representative or logging on to
Important Safety Information for EXCENEL RTU EZ: Persons with known hypersensitivity to penicillin or cephalosporins should avoid exposure to EXCENEL RTU EZ. Do not slaughter cattle or swine for 4 days following last treatment with this product. Using excess dosages, or administrating by unapproved routes, may result in illegal drug residues. Do not use in calves to be processed for veal.
See full prescribing information for EXCENEL RTU EZ here.
Important Safety Information for NAXCEL: As with all drugs, NAXCEL should not be used in animals found to be hypersensitive to the product. NAXCEL has a pre-slaughter withdrawal time of four days.
See full prescribing information for NAXCEL here.
About Zoetis
Zoetis (zō-EH-tis) is the leading animal health company, dedicated to supporting its customers and their businesses. Building on a 60-year history as the animal health business of Pfizer, Zoetis discovers, develops, manufactures and markets veterinary vaccines and medicines, complemented by diagnostic products and genetic tests and supported by a range of services. In 2012, the company generated annual revenues of $4.3 billion. With approximately 9,300 employees worldwide at the beginning of 2013, Zoetis has a local presence in approximately 70 countries, including 29 manufacturing facilities in 11 countries. Its products serve veterinarians, livestock producers and people who raise and care for farm and companion animals in 120 countries. For more information on the company, visit
Zoetis is the proud sponsor with the Smithsonian Institution Traveling Exhibition Service and the American Veterinary Medical Association of the mobile educational exhibit Animal Connections: Our Journey Together. Families visiting the exhibit will explore the vast bonds between people and animals and learn about the important role veterinarians play in protecting animal and human health. For more information, visit