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Quadripartite welcomes new antimicrobial resistance manifesto

Foreign Ministry of Oman Amr-conference-photo2-1-1024x589-1.jpeg
Global targets include reducing total amount of antimicrobials used in agrifood systems by at least 30-50% by 2030.

The recently concluded Third Global High-Level Ministerial Conference on Antimicrobial Resistance, hosted in Muscat, Oman, discussed for the first time targets to address the global antimicrobial resistance (AMR) challenge. The conference and its numerical targets for antimicrobial use in the human and animal sectors will pave the way for bold political commitments at the forthcoming UN General Assembly High-Level Meeting on AMR in 2024.

The conference agreed the Muscat Ministerial Manifesto, which sets out the three global targets:

  • Reduce the total amount of antimicrobials used in agrifood systems by at least 30-50% by 2030, galvanizing national and global efforts;
  • Preserve critically important antimicrobials for human medicine, ending the use of medically important antimicrobials for growth promotion in animals;
  • Ensure ‘Access’ group antibiotics (a category of antibiotics that are affordable, safe and have a low AMR risk) represent at least 60% of overall antibiotic consumption in humans by 2030.

According to The Food and Agriculture Organization of the United Nations (FAO), the UN Environment Programme (UNEP), the World Health Organization (WHO) and the World Organisation for Animal Health (WOAH, founded as OIE), known as the Quadripartite, globally agreed targets will be key to protecting the efficacy of antimicrobials and curbing the development of AMR worldwide, as well as reducing environmental pollution, in turn lowering the spread of AMR.

Countries also made commitments to implement National Action Plans for AMR and strengthen surveillance through improved data reporting and management, private sector engagement and implementation of evidence-based practices.

The Quadripartite organizations welcomed the outcomes of the conference for accelerating action on AMR.

The COVID-19 pandemic may have constrained global efforts to address AMR, but it has also demonstrated the critical links between humans, animals and the environmental ecosystem. A range of stakeholders – including the health care, pharmaceutical, veterinary, food safety, agricultural, environmental sectors – have a shared responsibility to continue to collectively respond to AMR.

“FAO recognizes the importance of reducing the need for antimicrobials on farms and will soon launch a global 10-year initiative to provide comprehensive support to Members focusing on transforming agrifood systems to contribute to this reduction,” said FAO Director-General QU Dongyu.

Under-Secretary-General of the United Nations and Executive Director for UNEP Inger Andersen commented, “Self-reporting by countries indicates that a third of National Action Plans on AMR do not include the environment. This signals the critical importance of supporting countries to boost actions to prevent and reduce environmental pollution. The burden of AMR can be reduced if we focus on all its dimensions and work together. UNEP is committed to working with Member States and key partners, including the Quadripartite organizations, to address AMR.”

WHO Director-General Dr. Tedros Adhanom Ghebreyesus said antimicrobial resistance is one of the most urgent and complex challenges of this time, “and yet perhaps because it is not as dramatic as a pandemic, a war or a humanitarian emergency, it doesn’t attract the same attention."

The conference marked the conclusion of World Antimicrobial Awareness Week, an annual week-long global campaign that brings together leaders across sectors to highlight the actions needed to preserve and protect antimicrobials.   

As highlighted by the Manifesto, the Quadripartite will continue to scale up support through a One Health approach, which balances and optimizes the health of people, animals, plants and ecosystems. The partnership will also continue to coordinate a global, multisectoral AMR response, promote strong governance and leadership, and support countries in developing and implementing National Action Plans on AMR.

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